Ta C A, Zee J A, Desrosiers T, Marin J, Levallois P, Ayotte P, Poirier G
Département des Sciences des Aliments et de Nutrition, Faculté des Sciences de l'Agriculture et de l'Alimentation, Université Laval, Ste-Foy, Québec, Canada.
Food Chem Toxicol. 1999 Dec;37(12):1147-51. doi: 10.1016/s0278-6915(99)00110-6.
The purpose of this study was to compare the effect of the nature and quantity of various dietary fibre (cellulose, hemicellulose, pectin, lignin) in diets on the binding capacity to pesticides azinphos-methyl (AZM), chlorpropham (CLP), chlorothalonil (CKL), permethrin (PER) as estimated by solubility under conditions of pH and temperature simulating those in the gastrointestinal tract (incubated at pH 2 for 30 min at 37 degrees C, then at pH 7 for 60 min). The ratios of fibre to pesticides were determined in omnivorous diets. In this model, the binding capacity of lignin was equal to hemicellulose for PER, AZM and CLP, but it was significantly higher for CKL. Hemicellulose bound more CKL, AZM and CLP than did cellulose. Although pectin appreciably decreased all pesticides, its effect was lower than other fibres with one exception--cellulose-CKL. In the presence of equal amounts of fibre, lignin exerted the most significant effect on pesticide solubility. Hemicellulose and cellulose bind to the same extent PER and AZM. The effect of pectin was significant only on CKL and AZM when compared to the control.
本研究的目的是比较日粮中各种膳食纤维（纤维素、半纤维素、果胶、木质素）的性质和数量对农药谷硫磷（AZM）、氯苯胺灵（CLP）、百菌清（CKL）、氯菊酯（PER）的结合能力，结合能力通过在模拟胃肠道条件下（在pH 2、37℃孵育30分钟，然后在pH 7孵育60分钟）的溶解度来估算。测定了杂食性日粮中纤维与农药的比例。在该模型中，木质素对PER、AZM和CLP的结合能力与半纤维素相当，但对CKL的结合能力显著更高。半纤维素比纤维素结合更多的CKL、AZM和CLP。尽管果胶能显著降低所有农药的含量，但其效果低于其他纤维，纤维素- CKL组合除外。在纤维含量相等的情况下，木质素对农药溶解度的影响最为显著。半纤维素和纤维素对PER和AZM的结合程度相同。与对照相比，果胶仅对CKL和AZM有显著影响。
