Blocker M E, Levine W C, St Louis M E
Epidemiology and Surveillance Branch, Division of STD Prevention, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Sex Transm Dis. 2000 Jan;27(1):53-9. doi: 10.1097/00007435-200001000-00011.
Among persons with a sexually transmitted disease (STD), the proportion who are also infected with HIV is a major factor influencing the public health impact of that STD on HIV transmission.
To assess HIV infection in persons with syphilis in the United States.
A systematic literature review was conducted of U.S. studies with HIV seroprevalence data in patients with syphilis.
Thirty studies were identified and analyzed. The median HIV seroprevalence in men and women infected with syphilis was 15.7% (interquartile range [IQR]: 13.6-21.8%), among men was 27.5% (23.1-29.6%), and among women was 12.4% (8.3-20.5%). Median odds ratios for men and women, men only, and women only were 4.5, 8.5, and 3.3, respectively. Seroprevalences among men who have sex with men (MSM) and injecting drug users (IDU) ranged from 64.3-90.0% and 22.5-70.6%, respectively.
Despite substantial variability, HIV seroprevalence is high among patients with syphilis in the United States, identifying them as a critical target group for HIV prevention efforts.
在性传播疾病（STD）患者中，同时感染HIV的比例是影响该性传播疾病对HIV传播的公共卫生影响的一个主要因素。
评估美国梅毒患者中的HIV感染情况。
对美国有关梅毒患者HIV血清阳性率数据的研究进行系统的文献综述。
共识别并分析了30项研究。感染梅毒的男性和女性中HIV血清阳性率的中位数为15.7%（四分位间距[IQR]：13.6 - 21.8%），男性为27.5%（23.1 - 29.6%），女性为12.4%（8.3 - 20.5%）。男性和女性、仅男性以及仅女性的中位数优势比分别为4.5、8.5和3.3。男男性行为者（MSM）和注射吸毒者（IDU）中的血清阳性率分别为64.3 - 90.0%和22.5 - 70.6%。
尽管存在很大差异，但美国梅毒患者中的HIV血清阳性率很高，这表明他们是HIV预防工作的关键目标群体。
