Burton D R, Parren P W
Department of Immunology and Molecular Biology, The Scripps Research Institute, La Jolla, California 92037, USA.
Nat Med. 2000 Feb;6(2):123-5. doi: 10.1038/72200.
Infection with some pathogens induces weak functional antibody responses that are non-protective, and there has been some skepticism about a role for antibodies in vaccine design. However, newer data show that antibodies can protect against infection with these pathogens, and new methods to elicit production of functional antibodies should be sought.
感染某些病原体可诱导产生微弱的、无保护作用的功能性抗体反应，并且对于抗体在疫苗设计中的作用一直存在一些怀疑。然而，最新数据表明抗体可以预防这些病原体的感染，因此应该寻找引发功能性抗体产生的新方法。
