Sharma S, Sharma M, Rathaur S
Department of Biochemistry, Faculty of Science, Banaras Hindu University, Varanasi, India.
Ann Trop Med Parasitol. 1999 Jun;93(4):379-87. doi: 10.1080/00034989958375.
The age- and sex-specific distributions of human infections with Wuchereria bancrofti were investigated at two sites in the Varanasi region of north India: one a rural, agricultural area (Chiraigaon) and the other an urban-slum area (Sunderpur). A random clinical and parasitological survey revealed that the prevalence of microfilaraemia and elephantiasis in the urban area (14% and 7.3%, respectively) were both higher than in the rural area (9% and 3.1%, respectively). In both areas, prevalence of microfilaraemia generally increased with age, to a maximum in those aged 20-29 years, and then declined. Within most age-groups, the prevalences of microfilaraemia and elephantiasis were higher in males than females. However, the prevalence of microfilaraemia in females from Chiraigaon who were aged > 30 years was higher than in their male counterparts. Though individual microfilarial intensities varied greatly, the geometric mean microfilarial intensity was higher in Sunderpur than in Chiraigaon (214 v. 196 microfilariae/ml). All 83 subjects with elephantiasis, except one in Sunderpur, were amicrofilaraemic. The present results indicate that bancroftian filariasis is one of the major public-health problems in the study area.
在印度北部瓦拉纳西地区的两个地点，对班氏吴策线虫人类感染的年龄和性别特异性分布进行了调查：一个是农村农业地区（奇莱冈），另一个是城市贫民窟地区（孙德布尔）。一项随机临床和寄生虫学调查显示，城市地区微丝蚴血症和象皮病的患病率（分别为14%和7.3%）均高于农村地区（分别为9%和3.1%）。在这两个地区，微丝蚴血症的患病率通常随年龄增长而增加，在20 - 29岁人群中达到最高，然后下降。在大多数年龄组中，男性的微丝蚴血症和象皮病患病率高于女性。然而，奇莱冈年龄大于30岁的女性微丝蚴血症患病率高于男性。尽管个体微丝蚴强度差异很大，但孙德布尔的微丝蚴几何平均强度高于奇莱冈（分别为214条/毫升和196条/毫升）。除孙德布尔的一名患者外，所有83名象皮病患者均无微丝蚴血症。目前的结果表明，班氏丝虫病是研究地区主要的公共卫生问题之一。
