Paya K, Rauhofer U, Rebhandl W, Deluggi S, Horcher E
Department of Pediatric Surgery, University of Vienna, Medical School, Waehringerguertel 18-20, A-1090 Vienna, Austria.
Surg Endosc. 2000 Feb;14(2):182-4. doi: 10.1007/s004649900096.
This pilot study was performed to reassess the widespread postulate that laparoscopic surgery is contraindicated in cases of perforating appendicitis.
A total of 75 children (appendiceal perforation: n = 67; perityphlic abscesses and peritonitis: n = 8) were analyzed in a prospective nonrandomized trial. Ten of them were treated by laparoscopic appendectomy.
In the laparoscopy group, both pain and hospitalization were less time-consuming (i.e., by 50% and 19%, respectively). Antibiotics use was down from 2.6 over 6 days to 2.2. over 5.5 days, while the duration of surgery was up by 52%. Wound healing disturbances occurred in 10% (n = 1) and postoperative fever in 50% (n = 5) of patients, compared to 14% (n = 9) and 15% (n = 10) in the group treated by open surgery. All severe complications requiring reintervention (10%; massive subcutaneous abscess, n = 3; retrocolic abscess, n = 2; adhesion-related ileus, n = 3; appendicular stump, n = 1) were associated with open surgery.
There was not a single major complication in the laparoscopy group. These unexpected results are in contrast to previous reports and have prompted us to initiate a prospective randomized trial.
本前瞻性非随机试验纳入了75例患儿(阑尾穿孔67例,盲肠周围脓肿和腹膜炎8例),旨在重新评估广泛存在的一种假设,即穿孔性阑尾炎患者禁忌行腹腔镜手术。
对其中10例患儿行腹腔镜阑尾切除术。
腹腔镜手术组患儿的疼痛时间和住院时间均缩短(分别缩短50%和19%)。抗生素使用时间从6天内2.6剂减少至5.5天内2.2剂,而手术时间延长了52%。腹腔镜手术组患儿伤口愈合障碍发生率为10%(1例),术后发热发生率为50%(5例);开放手术组上述发生率分别为14%(9例)和15%(10例)。所有需要再次干预的严重并发症(10%;巨大皮下脓肿3例、结肠后脓肿2例、粘连性肠梗阻3例、阑尾残端1例)均与开放手术有关。
腹腔镜手术组未发生严重并发症。这些意外结果与之前的报道相反,促使我们开展一项前瞻性随机试验。