Soames J V, Entwisle D N, Davies R M
J Periodontol. 1976 Aug;47(8):435-9. doi: 10.1902/jop.1976.47.8.435.
The spread of the inflammatory cell infiltrate in the progression of gingivitis to periodontitis in the Beagle dog follows the course of blood vessels. Buccolingually this is towards the periosteal surface of the bone and interdentally towards the midpoint and angles of the interdental septum. Interdentally the path of spread may be modified by the local anatomy. Bone resoprtion buccolingually progresses from the periosteal surface towards the tooth and interproximally along the crest of the interdental septa and within marrow spaces. The pathway of spread of the inflammatory cell infiltrate, the anatomic relationships of the teeth to each other and the original morphology of the alveolar bone may influence the pattern of bone loss in periodontitis.
在比格犬中,从牙龈炎进展到牙周炎时,炎性细胞浸润的扩散沿着血管路径进行。在颊舌侧,其朝着骨的骨膜表面扩散,而在牙间隙处则朝着牙间隙隔的中点和角部扩散。在牙间隙处,扩散路径可能会受到局部解剖结构的影响。颊舌侧的骨吸收从骨膜表面朝着牙齿方向进行,并且在牙间隙隔嵴处以及骨髓腔内沿牙间隙向近端发展。炎性细胞浸润的扩散途径、牙齿彼此之间的解剖关系以及牙槽骨的原始形态可能会影响牙周炎中骨质丧失的模式。