[恶性贫血：非洲的经验（3例报告）]

[Pernicious anemia: the African experience (3 cases reports)].

作者信息

Sidibé E H, Diop A N, Thiam A, Diop S

机构信息

Centre Marc-Sankale, Clinique médicale II, Service de médecine interne, BP 5062, Fann, Dakar, Sénégal.

出版信息

Sante. 1999 Sep-Oct;9(5):301-4.

PMID:10657774

Abstract

We report three cases of pernicious anemia diagnosed in women in Africa. All three women had macrocytic anemia with megaloblasts evident on medullogram. The patients had neurological signs of combined sclerosis and the presence of megaloblasts confirmed the diagnosis of pernicious anemia. All were successfully treated parenterally with vitamins. This disease seems to be underdiagnosed in Africa given the number of cases reported in previous studies.

摘要

我们报告了在非洲女性中诊断出的三例恶性贫血病例。所有三名女性均患有大细胞性贫血，骨髓涂片显示巨幼细胞明显。患者有合并性硬化的神经学体征，巨幼细胞的存在证实了恶性贫血的诊断。所有患者均通过肠胃外补充维生素成功治愈。鉴于先前研究报告的病例数量，这种疾病在非洲似乎未得到充分诊断。