Krueger J A, Davis R B, Field C
Obstet Gynecol. 1976 Sep;48(3):324-7.
Acute leukemia associates with pregnancy is relatively uncommon, and because of the age distribution of patients with acute leukemia the majority have had acute granulocytic leukemia. Various combinations of chemotherapeutic agents are commonly employed now to obtain maximal benefit, related to differing pharmacologic activities of single agents. The present case documents the use of multiple cytotoxic drugs in the management of acute lymphocytic leukemia, with successful delivery of a normal infant. In this patient severe anemia and potentially teratogenic drugs did not appear to affect the fetus.
急性白血病合并妊娠相对少见，由于急性白血病患者的年龄分布特点，大多数为急性粒细胞白血病。目前通常采用多种化疗药物联合使用，以获得最大益处，这与单一药物不同的药理活性有关。本病例记录了在急性淋巴细胞白血病治疗中使用多种细胞毒性药物，并成功分娩出一名正常婴儿。在该患者中，严重贫血和潜在致畸药物似乎并未影响胎儿。
