Chaffange P, Valignat C, Ruffion A, Archimbaud J P
Service d'Urologie, Hôpital de l'Antiquaille, Lyon France.
Prog Urol. 1999 Dec;9(6):1113-6.
The authors report a case of eosinophilic cystitis with a very acute course after partial cystectomy, requiring semi-urgent total cystoprostatectomy with ileal bladder replacement. The patient is completely asymptomatic ten years after the operation. This case can be classified with the pseudoneoplastic forms of interstitial cystitis occurring in patients with a history of urological surgery. The two-stage course of the disease suggests the combination of two pathophysiological mechanisms: repeated aggression to the urothelial wall responsible for an intense inflammatory reaction and allergy to suture material, accounting for the subsequent rapid development.
作者报告了1例嗜酸性膀胱炎病例,该病例在膀胱部分切除术后病程极为凶险,需要半急诊行全膀胱前列腺切除术并回肠膀胱替代术。术后10年患者完全无症状。该病例可归类为有泌尿外科手术史患者发生的间质性膀胱炎假肿瘤形式。疾病的两阶段病程提示两种病理生理机制共同作用:对膀胱上皮壁的反复侵袭导致强烈炎症反应,以及对缝合材料过敏,这解释了随后疾病的快速进展。