Aktan M, Büyükmumcu M, Seker M, Mermer S, Duman S
Department of Histology and Embryology, Faculty of Medicine, University of Selçuk, Konya, Turkey.
Kaibogaku Zasshi. 1999 Dec;74(6):639-42.
In this study, the morphometric differences of the different dermis regions during the development of the human fetus were investigated. The different dermis regions, namely, cranial, femoral and plantar (sole) parts of 40 fetuses which were between 12th-23.5th week gestation age were obtained from maternity hospital and after the routine H&E histological procedure, the measurement was performed with ocular micrometer. The first sharp increase was observed in the dermis of cranial region. It has been suggested that the thickness of the dermis is dependent on the collagen and elastic fibres, but the flexibility of the dermis is dependent on the number and the structure of the elastic fibres. The early beginning of the increase of the dermis thickness in the cranial part may be due to the effect of the cranio-caudal stimulation on the production of the collagen and elastic fibres in the embryonic term.
在本研究中，对人类胎儿发育过程中不同真皮区域的形态计量学差异进行了研究。从妇产医院获取了40例妊娠年龄在12至23.5周之间胎儿的不同真皮区域，即头部、股骨和足底（脚掌）部分。经过常规苏木精-伊红（H&E）组织学处理后，使用目镜测微计进行测量。在头部区域的真皮中观察到首次急剧增加。有人提出，真皮的厚度取决于胶原纤维和弹性纤维，但真皮的柔韧性取决于弹性纤维的数量和结构。头部真皮厚度增加的早期开始可能是由于胚胎期头尾刺激对胶原纤维和弹性纤维产生的影响。
