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近距离放射治疗源周围几何因子测定中点源和线源近似法的局限性。

Limitations of the point and line source approximations for the determination of geometry factors around brachytherapy sources.

作者信息

Karaiskos P, Sakelliou L, Sandilos P, Vlachas L

机构信息

Physics Department, University of Athens, Greece.

出版信息

Med Phys. 2000 Jan;27(1):124-8. doi: 10.1118/1.598873.

Abstract

Geometry factors were calculated around commercially available pellets and elongated brachytherapy sources taking into account their actual active core geometries. These calculations were compared with corresponding ones derived using the point and line source approximations commonly used for the determination of geometry factors, as proposed by AAPM Task Group 43. The point source approximation was found to be efficient for the determination of geometry factors around single active pellets, even at radial distances very close to the source. It is also valid for the determination of geometry factors at radial distances r>2L from elongated brachytherapy sources of length L. For smaller radial distances, however, this approximation introduces significant errors, >50%, around elongated source designs, thus being unacceptable for the determination of geometry factors in this case. The line source approximation was found to accurately reproduce geometry factors around elongated brachytherapy source designs. Errors greater than 3%, due to the fact that the line source approximation ignores the radial dimension d of the source, are observed only at radial distances very close to the source (r< or =L/2), at polar angles far away from their transverse bisectors. These errors depend on the ratio d/L and increase as this ratio increases.

摘要

考虑到市售粒籽源和延长型近距离放射治疗源的实际活性核心几何形状,计算了它们周围的几何因子。按照美国医学物理学家协会任务组43的提议,将这些计算结果与使用通常用于确定几何因子的点源和线源近似法得出的相应结果进行了比较。发现点源近似法对于确定单个活性粒籽源周围的几何因子是有效的,即使在非常靠近源的径向距离处也是如此。它对于确定长度为L的延长型近距离放射治疗源在径向距离r>2L处的几何因子也是有效的。然而,对于较小的径向距离,这种近似法在延长型源设计周围会引入>50%的显著误差,因此在这种情况下用于确定几何因子是不可接受的。发现线源近似法能够准确再现延长型近距离放射治疗源设计周围的几何因子。由于线源近似法忽略了源的径向尺寸d,仅在非常靠近源(r≤L/2)且极角远离其横向平分线的径向距离处观察到大于3%的误差。这些误差取决于d/L的比值,并且随着该比值的增加而增大。

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