Lewinsohn P M, Rohde P, Brown R A
Oregon Research Institute, Eugene 97403-1983, USA.
Addiction. 1999 Jun;94(6):913-21. doi: 10.1046/j.1360-0443.1999.94691313.x.
This study examined the impact of adolescent cigarette smoking (life-time use, recency, frequency and age of onset) on the occurrence of substance use disorders during young adulthood.
Participants were assessed while in high school (T1), approximately 1 year later (T2) and then after they had turned 24 years of age (T3).
Adolescents were randomly selected at T1 from nine senior high schools in western Oregon.
A subset (n = 684) of 1709 adolescents who had been assessed regarding cigarette smoking during high school were evaluated for alcohol, cannabis and other drug abuse/dependence up to age 24.
Semi-structured interviews provided information regarding life-time use of cigarettes and chewing tobacco, age of smoking onset, frequency and quantity of cigarette smoking and quit efforts in adolescence. Diagnoses of substance abuse and dependence in young adulthood were made as per DSM-IV.
Life-time smoking among older adolescents significantly increased the probability of future alcohol, cannabis, hard drug and multiple drug use disorders during young adulthood. Having been a former smoker did not reduce the risk of future substance use disorder, although having maintained smoking cessation for more than 12 months was associated with significantly lower rates of future alcohol use disorder. Daily smoking was associated with increased risk of future cannabis, hard drug and multiple drug use disorders. Among daily smokers, earlier smoking onset age predicted future substance use disorders.
The results extend knowledge about relationships between cigarette smoking during adolescence and the development of substance use disorders during young adulthood, illustrating additional risks associated with early cigarette smoking. Future research is needed to examine potential causal associations.
本研究探讨青少年吸烟(终生吸烟情况、近期吸烟情况、吸烟频率及开始吸烟年龄)对青年期物质使用障碍发生情况的影响。
在参与者高中时(T1)、大约1年后(T2)以及满24岁后(T3)对其进行评估。
在俄勒冈州西部的9所高中,于T1阶段随机选取青少年。
从1709名在高中时接受过吸烟情况评估的青少年中抽取一个子集(n = 684),对他们在24岁之前的酒精、大麻及其他药物滥用/依赖情况进行评估。
半结构化访谈提供了有关终生吸烟及嚼烟情况、开始吸烟年龄、吸烟频率和数量以及青少年戒烟尝试的信息。根据《精神疾病诊断与统计手册》第四版(DSM-IV)对青年期的物质滥用和依赖进行诊断。
年龄较大的青少年终生吸烟显著增加了其在青年期未来出现酒精、大麻硬毒品及多种药物使用障碍的可能性。曾经吸烟并未降低未来物质使用障碍的风险,不过戒烟超过12个月与未来酒精使用障碍发生率显著降低相关。每日吸烟与未来大麻、硬毒品及多种药物使用障碍风险增加相关。在每日吸烟者中,较早的开始吸烟年龄预示着未来会出现物质使用障碍。
这些结果扩展了关于青少年吸烟与青年期物质使用障碍发展之间关系的认识,说明了早期吸烟带来的额外风险。需要进一步的研究来检验潜在的因果关联。