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丙酸倍氯米松吸入治疗气管插管后气管狭窄

Beclomethasone diproprionate inhalation as a treatment for post-intubation tracheal stenosis.

作者信息

Abo M, Fujimura M, Kibe Y, Kida H, Matsuda T

机构信息

Department of Internal Medicine, National Kanazawa Hospital, Japan.

出版信息

Int J Clin Pract. 1999 Apr-May;53(3):217-8.

Abstract

A 67-year-old man was intubated for one week and suffered from wheeze and dyspnoea three months after the extubation. Bronchoscopy revealed tracheal stenosis by a web, which subsequent biopsy showed to be granulation tissue. The stenosis was removed by laser therapy but the stenosis soon returned. As cardiac function was poor, beclomethasone diproprionate (BDP) inhalation therapy (1200 micrograms daily) was started and proved successful. Discontinuation of inhalation therapy resulted in restenosis. Steroid inhalation therapy may be able to control post-intubation tracheal stenosis caused by granulation tissue.

摘要

一名67岁男性插管一周,拔管三个月后出现喘息和呼吸困难。支气管镜检查显示气管因纤维带而狭窄,随后的活检显示为肉芽组织。通过激光治疗去除了狭窄,但狭窄很快复发。由于心脏功能较差,开始使用丙酸倍氯米松(BDP)吸入治疗(每日1200微克),并证明有效。停止吸入治疗导致再狭窄。类固醇吸入治疗可能能够控制由肉芽组织引起的插管后气管狭窄。

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