Kardaszewicz E, Siejeńska L
Pol Med Sci Hist Bull (1973). 1976 Apr-Jun;15(2):225-9.
In 16 patients with chronic myelocytic leukemia an attempt to retard the myeoblastic transformation was carried out by means of repeated BCG administration in the period of remissions resulting from chemotherapy. Vaccinations were repeated at intervals of 4 weeks with doses of 2 mg of Mycobacteria by scarification. The time of uninterrupted remissions maintained with BCG vaccinations only ranged from 2 to 28 months, on the average 7.4 months. In this group 2 patients died and the duration of follow-up in the remaining cases ranges from 16 to 106 months, average 43.5 months. The survival time in the group of 16 patients with the same disease, who died after treatment with cytostatics only, was shorter ranging from 12 to 83 months, 32 months on the average. In one patient BCG vaccination was followed by tuberculosis of a supraclavicular lymph node.
对16例慢性粒细胞白血病患者，在化疗诱导缓解期通过反复接种卡介苗（BCG）尝试延缓其髓母细胞转化。每隔4周进行一次接种，通过划痕法给予2mg分枝杆菌。仅通过卡介苗接种维持的持续缓解时间为2至28个月，平均7.4个月。该组中有2例患者死亡，其余病例的随访时间为16至106个月，平均43.5个月。16例患有相同疾病且仅接受细胞抑制剂治疗后死亡的患者，其生存时间较短，为12至83个月，平均32个月。1例患者接种卡介苗后发生锁骨上淋巴结结核。
