Helfrick D L, Grinzaid K A, Brown A L, Fernhoff P M
Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.
J Med Assoc Ga. 1999 Dec;88(4):38-40.
The main objectives were to describe the epidemiology of primary congenital hypothyroidism (CH) in Georgia during the past 20 years and specifically to determine whether there was a significant increase in CH prevalence proximal to the Savannah River Site (SRS), a nuclear plant.
Data were derived from the Georgia Newborn Screening Program. Frequencies were determined for race, sex, birth weight and birth month. Seasonality effects were investigated and the prevalence was determined and mapped by health district.
The majority of the CH cases were female, white and of average birth weight. The sex ratio varied by race/ethnicity. There was not a statistically significant increase in the prevalence in the eastern districts that were in close proximity to the SRS.
Although there were differences in the prevalence between health districts, we found no increased prevalence of CH in those health districts proximal to the SRS.
主要目的是描述佐治亚州过去20年原发性先天性甲状腺功能减退症（CH）的流行病学情况，特别是确定核电站萨凡纳河厂址（SRS）附近CH的患病率是否显著增加。
数据来源于佐治亚州新生儿筛查项目。确定了种族、性别、出生体重和出生月份的频率。调查了季节性影响，并按健康区确定和绘制了患病率。
大多数CH病例为女性、白人且出生体重平均。性别比因种族/民族而异。在靠近SRS的东部地区，患病率没有统计学上的显著增加。
虽然各健康区之间的患病率存在差异，但我们发现SRS附近的那些健康区中CH的患病率没有增加。
