Petersen P H
Department of Clinical Biochemistry, Odense University Hospital, Denmark.
Scand J Clin Lab Invest. 1999 Nov;59(7):517-21. doi: 10.1080/00365519950185265.
The graphical model for evaluation of analytical requirements for bimodal distributions, based on probit transformation and calculation of false-positive and false-negative results for assumed random and systematic analytical errors, is presented in theory. It is concluded that the bimodal model is an excellent tool for evaluation of the effect of analytical quality and, therefore, useful for estimation of analytical quality specifications for quantities used in specific clinical strategies and situations as well as based on analysis of clinical outcome.
基于概率单位变换以及针对假定的随机和系统分析误差计算假阳性和假阴性结果的双峰分布分析要求评估图形模型在理论上已被提出。得出的结论是,双峰模型是评估分析质量影响的优秀工具,因此,对于估计特定临床策略和情况中使用的量的分析质量规范以及基于临床结果分析而言是有用的。