Antimycobacterial activity of new ortho-, meta- and para-toluidine derivatives.
作者信息
Biava M, Fioravanti R, Porretta G C, Sleiter G, Deidda D, Lampis G, Pompei R
机构信息
Dipartimento di Studi di Chimica e Tecnologia delle Sostanze Biologicamente Attive, Università La Sapienza, Rome, Italy.
出版信息
Farmaco. 1999 Nov-Dec;54(11-12):721-7. doi: 10.1016/s0014-827x(99)00084-1.
Abstract
Novel toluidine derivatives are described. Some of them showed an interesting in vitro activity against Mycobacterium tuberculosis, M. smegmatis, M. marinum, M. gordonae, and M. avium. Some of them were more active than Streptomycin and Isoniazid, which were used as controls, against M. avium and M. gordonae. In particular, we confirm the good activity of biphenyl derivatives.
摘要
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