Wang S J, Fuh J L, Lu S R, Liu C Y, Hsu L C, Wang P N, Liu H C
Neurological Institute, Veterans General Hospital-Taipei, and Department of Neurology, Taiwan.
Neurology. 2000 Jan 25;54(2):314-9. doi: 10.1212/wnl.54.2.314.
To investigate the prevalence, risk factors, and prognosis of chronic daily headache (CDH) in a population of elderly Chinese subjects.
A community-based survey of registered residents > or =65 years old (n = 2,003) in two townships of Kinmen Island in 1993. A neurologist used a structured questionnaire and clinical interview to make the diagnosis of headache. Subjects who had headaches > or =15 days/month for > or =6 months in the previous year were considered to have CDH. CDH was further classified into chronic tension-type headache (CTTH), CDH with migrainous features (CDH/MF), and other CDH. Person-to-person biannual follow-up of the subjects with CDH was done in June 1995 and August 1997.
A total of 1,533 people (77%) participated in our prevalence study. Sixty subjects (3.9%) fulfilled the criteria for CDH, with a higher prevalence in women (F/M: 5.6%/1.8%, p < 0.001). Of these subjects, 42 (70%) had CTTH, 15 (25%) had CDH/MF, and 3 (5%) had other CDH. Only 23% of those with CDH had consulted physicians for their headaches in the previous year. Multivariate logistic regression revealed the significant risk factors for CDH to be analgesic overuse (OR = 79), a history of migraine (OR = 6.6), and a Geriatric Depression Scale-Short Form score of > or =8 (OR = 2.6). The follow-up results in 1995 and 1997 showed that about two-thirds of the subjects still had CDH. Analgesic overuse (relative risk = 1.6) in 1993 was a significant predictor of persistent CDH at follow-up.
A total of 3.9% of this elderly population had CDH, with CTTH being the most common subtype. Almost two-thirds of those with CDH had persistent frequent headaches at follow-up. Analgesic overuse was a significant predictor of a poor outcome.
调查中国老年人群中慢性每日头痛(CDH)的患病率、危险因素及预后情况。
1993年对金门岛两个乡镇65岁及以上的登记居民(n = 2,003)进行基于社区的调查。由一名神经科医生使用结构化问卷并进行临床访谈来诊断头痛。在前一年中每月头痛≥15天且持续≥6个月的受试者被视为患有CDH。CDH进一步分为慢性紧张型头痛(CTTH)、具有偏头痛特征的CDH(CDH/MF)和其他CDH。1995年6月和1997年8月对患有CDH的受试者进行了每年两次的随访。
共有1,533人(77%)参与了我们的患病率研究。60名受试者(3.9%)符合CDH标准,女性患病率更高(女/男:5.6%/1.8%,p < 0.001)。在这些受试者中,42人(70%)患有CTTH,15人(25%)患有CDH/MF,3人(5%)患有其他CDH。在前一年中,只有23%的CDH患者因头痛咨询过医生。多因素logistic回归显示,CDH的显著危险因素为镇痛药过度使用(比值比[OR] = 79)、偏头痛病史(OR = 6.6)以及老年抑郁量表简表得分≥8(OR = 2.6)。1995年和1997年的随访结果显示,约三分之二的受试者仍患有CDH。1993年的镇痛药过度使用(相对危险度 = 1.6)是随访时持续性CDH的显著预测因素。
该老年人群中共有3.9%患有CDH,其中CTTH是最常见的亚型。在随访中,近三分之二的CDH患者持续频繁头痛。镇痛药过度使用是预后不良的显著预测因素。