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[儿童白血病的诊断与治疗方面]

[Diagnostic and therapeutic aspects of leukoses in childhood].

作者信息

Aurich G, Plenert W, Zintl F

出版信息

Z Gesamte Inn Med. 1976 Apr 15;31(8):240-3.

PMID:1066873
Abstract

30 TO 40% of all malignant neoformations in childhood are leukaemias. Within this group 80 to 85% of acute lymphatic leukaemias are found. The indicating signs (conditioned by the suppression of the normal myelopoiesis) are briefly described, differential diagnosies are only mentioned. Primary diagnostics and diagnostics of the course, the principles of remission induction and continuous therapy in leucaemia are sketchily described. Treatment of acute lymphatic leukaemia is performed adequate to the therapeutic scheme after Pinkel Prophylaxis of the central nervous system must be demanded. Modern therapeutic methods with the help of synchronisation and oncobiogramme are demonstrated. The possibilities of the symptomatic therapy in disease-conditioned and therapy-conditioned complications and side-effects occupy a somewhat broader space. Finally the principles of the organisation of the treatment of leukaemia in childhood are described.

摘要

儿童期所有恶性肿瘤中,30%至40%为白血病。在这一组中,发现80%至85%为急性淋巴细胞白血病。简要描述了(由正常骨髓生成受抑制引起的)指示性体征,仅提及鉴别诊断。简要描述了白血病的初步诊断及病程诊断、缓解诱导和持续治疗的原则。急性淋巴细胞白血病的治疗按照平克尔之后的治疗方案进行,必须要求对中枢神经系统进行预防。展示了借助同步化和肿瘤生物图谱的现代治疗方法。对症治疗在疾病相关和治疗相关并发症及副作用方面的可能性占据了较为广阔的篇幅。最后描述了儿童白血病治疗组织的原则。

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