使用双头符合伽马相机进行脑氟-18氟脱氧葡萄糖成像：与专用环形探测器正电子发射断层扫描的比较。
Brain fluorine-18 fluorodeoxyglucose imaging with dual-head coincidence gamma camera: comparison with dedicated ring-detector positron emission tomography.
作者信息
Fukuchi K, Hayashida K, Moriwaki H, Fukushima K, Kume N, Katafuchi T, Sago M, Takamiya M, Ishida Y
机构信息
Department of Radiology, National Cardiovascular Center, Suita, Osaka, Japan.
出版信息
AJNR Am J Neuroradiol. 2000 Jan;21(1):99-104.
BACKGROUND AND PURPOSE
Dual-head coincidence gamma camera (DHC) imaging has been proposed as an alternative to dedicated ring-detector positron emission tomography (dr-PET) for clinical fluorodeoxyglucose (FDG) studies. The purpose of this investigation was to assess the quality of DHC images in FDG studies of the human brain.
METHODS
Seven healthy volunteers and 12 patients with various cerebral disorders underwent consecutive brain dr-PET and DHC with FDG. All sets of images were compared semiquantitatively using regions of interest.
RESULTS
Cortical count ratios to the cerebellum on DHC and dr-PET images did not differ significantly among the volunteers, except in the superior frontal cortex and thalamus. In all studies including those of cerebral disorders, the mean cortical-to-cerebellar ratios of DHC and dr-PET images correlated closely.
CONCLUSION
FDG imaging with DHC delineated the metabolic distribution of glucose in the brain as well as dr-PET did, except in the superior frontal cortex and thalamus. Therefore, DHC may be a dedicated cost-effective means of detecting metabolic abnormalities in the brain.
背景与目的
双头符合伽马相机（DHC）成像已被提议作为专用环形探测器正电子发射断层扫描（dr-PET）用于临床氟脱氧葡萄糖（FDG）研究的替代方法。本研究的目的是评估人脑FDG研究中DHC图像的质量。
方法
7名健康志愿者和12名患有各种脑部疾病的患者接受了连续的脑部dr-PET和FDG DHC检查。使用感兴趣区域对所有图像集进行半定量比较。
结果
除额上回和丘脑外，志愿者的DHC和dr-PET图像上皮质与小脑的计数比无显著差异。在所有研究中，包括脑部疾病的研究，DHC和dr-PET图像的平均皮质与小脑比值密切相关。
结论
除额上回和丘脑外，DHC的FDG成像在描绘脑内葡萄糖代谢分布方面与dr-PET一样好。因此，DHC可能是检测脑部代谢异常的一种经济有效的专用手段。
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