Powell L J
Am J Med Technol. 1979 Feb;45(2):138-42.
C-reactive protein (CRP) is an acute-phase protein present in normal serum which increases significantly with tissue necrosis of inflammation. Presented in this review is a history of investigations of the protein, and its physical, immunological, and functional characteristics, as well as the various methods used for its detection and quantitation. The relationship of CRP to other acute-phase reactants is summarized with respect to its value in clinical diagnosis. The clinical application of CRP in detecting and monitoring post-surgical complications and in helping detect various disease states is also discussed.
C反应蛋白（CRP）是正常血清中存在的一种急性期蛋白，其水平会随着炎症组织坏死而显著升高。本文回顾了该蛋白的研究历史、其物理、免疫和功能特性，以及用于检测和定量的各种方法。总结了CRP与其他急性期反应物的关系及其在临床诊断中的价值。还讨论了CRP在检测和监测术后并发症以及帮助检测各种疾病状态方面的临床应用。
