Ferrari T C, Couto C A, Murta-Oliveira C, Conceição S A, Silva R G
Dept. of Internal Medicine, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Scand J Gastroenterol. 2000 Jan;35(1):108-9. doi: 10.1080/003655200750024623.
Actinomycosis is an uncommon entity, caused by an anaerobic bacterium, Actinomyces israelii, which is a component of the human oral and gastrointestinal flora. The cervicofacial region is the commonest site of disease, and the abdomen is the second commonest. In this situation the disease is almost always unifocal and restricted to the right colon, especially to the cecum. We report here the case of a patient with a very rare form of this entity, characterized by multiple foci of abdominal involvement with the most severe lesions localized in the transverse and sigmoid colon. The clinical presentation resembled a picture of colon perforation by cancer or diverticulitis, and the diagnosis was made by histopathologic examination of the lesions removed at surgery. No predisposing factor was found. The infection was successfully treated with a prolonged course of penicillin, after the surgical removal of the lesions.
放线菌病是一种罕见的疾病，由厌氧细菌以色列放线菌引起，该菌是人类口腔和胃肠道菌群的组成部分。 cervicofacial区域是最常见的发病部位，腹部是第二常见的发病部位。在这种情况下，疾病几乎总是单灶性的，局限于右结肠，尤其是盲肠。我们在此报告一例这种罕见疾病的病例，其特征是腹部有多个受累病灶，最严重的病变位于横结肠和乙状结肠。临床表现类似于癌症或憩室炎导致的结肠穿孔，通过手术切除病变的组织病理学检查做出诊断。未发现诱发因素。在手术切除病变后，通过延长青霉素疗程成功治疗了感染。
