Effects of sodium trimetaphosphate supplementation of a high sucrose diet on the microbial and biochemical composition of four-day plaque and on urine calcium and phosphorus levels.

Daily supplementation of a high sucrose diet with 5 gm TMP resulted in significant alterations in certain human plaque components. Veillonella and Neisseria population (as percent total viable microorganisms), S sanguis (as percent streptococci), and levan hydrolase activity per milligram of plaque increased, whereas total viable microorganisms per milligram of plaque, streptococci per milligram of plaque, and specific fructosyltransferase activity decreased during the TMP-containing diet regimen.