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[31例接受改良式全大脑半球切除术治疗婴儿偏瘫性癫痫的长期疗效]

[Long-term results in 31 patients on total hemispherectomy modified for infantile hemiplegic epilepsy].

作者信息

Xu Y, Li S, Chen B

机构信息

Department of Neurosurgery, Beijing Tiantan Hospital.

出版信息

Zhonghua Wai Ke Za Zhi. 1997 Jul;35(7):421-4.

PMID:10677977
Abstract

To overcome long-term complications of hemispherectomy, We modified its operative method. The modified hemispherectomy was performed for 31 patients between 1985 and 1992. These patients were studied for 7 years after operation. The results showed total control of seizures in 28 children with chronic epilepsy (90%) or near-total control in the others. No deaths or delayed complications were noted but improvement in behavior and hemiplegia. CT and MRI showed marked shift of the remaining hemisphere. On brain-stem auditory evoked potentials, the latency of peak I was not variant (P > 0.05). The method makes the insulation of the subdural cavity from the ventricular system more reliable, and climates the pathological conditions.

摘要

为克服大脑半球切除术的长期并发症,我们改进了其手术方法。1985年至1992年间,对31例患者实施了改良大脑半球切除术。术后对这些患者进行了7年的研究。结果显示,28例慢性癫痫患儿的癫痫发作得到完全控制(90%),其他患儿接近完全控制。未发现死亡或延迟性并发症,但行为和偏瘫有所改善。CT和MRI显示剩余半球有明显移位。脑干听觉诱发电位显示,I波峰潜伏期无变化(P>0.05)。该方法使硬脑膜下腔与脑室系统的隔离更可靠,并改善了病理状况。

相似文献

1
[Long-term results in 31 patients on total hemispherectomy modified for infantile hemiplegic epilepsy].[31例接受改良式全大脑半球切除术治疗婴儿偏瘫性癫痫的长期疗效]
Zhonghua Wai Ke Za Zhi. 1997 Jul;35(7):421-4.
2
[Modified hemispherectomy for intractable epilepsy in patients with infantile hemiplegia].[改良半球切除术治疗小儿偏瘫患者的顽固性癫痫]
Zhonghua Wai Ke Za Zhi. 2005 Nov 1;43(21):1410-3.
3
Outcome after hemispherectomy in hemiplegic adult patients with refractory epilepsy associated with early middle cerebral artery infarcts.成年偏瘫患者因大脑中动脉早期梗死伴难治性癫痫行大脑半球切除术后的结局
Epilepsia. 2009 Jun;50(6):1381-4. doi: 10.1111/j.1528-1167.2008.01795.x. Epub 2008 Oct 6.
4
Hemispherectomy for the treatment of epilepsy and behavior disturbance.大脑半球切除术治疗癫痫和行为障碍。
Can J Neurol Sci. 1980 Feb;7(1):33-8.
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Functional hemispherectomy for treatment of epilepsy associated with hemiplegia: rationale, indications, results, and comparison with callosotomy.功能性大脑半球切除术治疗偏瘫相关性癫痫:理论依据、适应证、疗效及与胼胝体切开术的比较
Ann Neurol. 1988 Jul;24(1):27-34. doi: 10.1002/ana.410240107.
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[Treatment of intractable epilepsy with hemispherectomy].[大脑半球切除术治疗难治性癫痫]
Zhonghua Wai Ke Za Zhi. 2003 May;41(5):359-61.
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Functional hemispherectomy in children.儿童功能性大脑半球切除术
Neuropediatrics. 1993 Feb;24(1):53-5. doi: 10.1055/s-2008-1071514.
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Cerebral hemispherectomy in pediatric patients with epilepsy: comparison of three techniques by pathological substrate in 115 patients.小儿癫痫患者的大脑半球切除术:115例患者基于病理基础的三种技术比较
J Neurosurg. 2004 Feb;100(2 Suppl Pediatrics):125-41. doi: 10.3171/ped.2004.100.2.0125.
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Long-term P300 in hemispherectomized patients.大脑半球切除术患者的长期 P300。
Chin Med J (Engl). 2009 Aug 5;122(15):1769-74.
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Hemispherectomy for intractable epilepsy in adults: the first reported series.成人难治性癫痫的大脑半球切除术:首个报告系列病例
Ann Neurol. 2007 Apr;61(4):372-6. doi: 10.1002/ana.21084.

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Ipsilateral and contralateral auditory brainstem response reorganization in hemispherectomized patients.大脑半球切除患者同侧和对侧听觉脑干反应的重组
Neural Plast. 2013;2013:832473. doi: 10.1155/2013/832473. Epub 2013 Dec 23.