Roane D M, Feinberg T E, Meckler L, Miner C R, Scicutella A, Rosenthal R N
Department of Psychiatry and the Neurobehavior and Alzheimer's Disease Center, Beth Israel Medical Center, New York, NY 10003, USA.
J Neuropsychiatry Clin Neurosci. 2000 Winter;12(1):40-3. doi: 10.1176/jnp.12.1.40.
The authors describe the use of gabapentin in the treatment of 4 outpatients with dementia-associated agitation. On the basis of clinical case reports and the Overt Agitation Severity Scale, all 4 patients had reduced agitation with gabapentin. Three of 4 patients were successfully titrated to a full dose of 2,400mg/day. These findings suggest a possible role for gabapentin in the behavioral management of patients with dementia.