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[Changes in the lipid profile and thyroid function in adult patients with hypopituitarism after substitutive treatment with growth hormone].

作者信息

Gómez Sáez J M, Gómez Arnaiz N, Soler Ramón J

机构信息

Servicio de Endocrinología, Ciutat Sanitària i Universitària de Bellvitge, L'Hospitalet de Llobregat, Barcelona.

出版信息

Med Clin (Barc). 1999 Dec 11;113(20):775-6.

PMID:10680141
Abstract

BACKGROUND

Adult growth hormone (GH) deficiency is associated with changes in serum lipid levels that can modify after GH substitution.

METHODS

We studied 18 patients with GH deficiency treated with GH for 18 or 24 months.

RESULTS

A decrease of total cholesterol, LDL with an increase in HDL without triglycerides changes was observed. T4 levels decreased and T3 increased.

CONCLUSIONS

The GH substitution treatment in patients with GH deficiency improves the lipid profile and promotes the T4 to T3 conversion.

摘要

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