Lu R, Wang N, Zhao J
Nanjing Railway Medical College.
Zhonghua Fu Chan Ke Za Zhi. 1998 Mar;33(3):168-9.
To explore the postoperative changes in the cultures of ureaplasma urealyticum (UU), mycoplasma hominis (Mh), L-form bacteria (L-form), anaerobic bacteria (Ana) and chlamydia trochomatis (CT) after intrauterine operation.
Four groups of patients were set up: group 1, induced abortion; group 2, intrauterine device (IUD) insertion; group 3, penicillin i.m. after IUD insertion; group 4, oral lincomycin after IUD insertion. Intrauterine secretion were aspirated to identify the above microbes before operation and within 1 week of ending of menstrual bleeding for 4 consecutive postoperative cycles. Bacteria-carrier was defined as at least one of the 5 microbes detected.
No difference was shown in the incidence of bacteria-carrier (IBC) among the 4 groups preoperation. The IBC tended to be the highest in the first menstrual cycle postsurgery in all the 4 groups, then decreased. Compared with preoperation, there were significantly higher IBC in the 3 IUD groups (P < 0.05) except group 1.
IUD is a major factor for intrauterine microbes existing after operation, and the natural body defense system can help to get rid of the organism by time. Small doses and short period of penicillin or lincomycin administration proved not effective in clearing the intrauterine microbes after IUD insertion.
探讨宫腔手术后解脲脲原体(UU)、人型支原体(Mh)、L型细菌(L-form)、厌氧菌(Ana)及沙眼衣原体(CT)培养结果的术后变化。
设立四组患者:第1组,人工流产;第2组,放置宫内节育器(IUD);第3组,放置IUD后肌肉注射青霉素;第4组,放置IUD后口服林可霉素。在术前及术后连续4个月经周期月经出血结束后1周内抽吸宫腔分泌物以鉴定上述微生物。细菌携带者定义为检测到5种微生物中的至少一种。
四组术前细菌携带者发生率(IBC)无差异。所有四组术后第一个月经周期IBC往往最高,然后下降。与术前相比,除第1组外,其他3个IUD组IBC显著更高(P<0.05)。
IUD是术后宫腔内微生物存在的主要因素,机体自然防御系统可随时间推移帮助清除微生物。小剂量、短疗程应用青霉素或林可霉素对放置IUD后清除宫腔内微生物无效。