Li S, Zhang X, Han G
Institute for Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing.
Zhonghua Liu Xing Bing Xue Za Zhi. 1999 Aug;20(4):208-11.
To study the risk factors for pulmonary tuberculosis (PTB) in the servicemen of armed forces and lay a basis for its prevention and control.
A 1:2 matched case-control study was carried cut in the servicemen, with 86 cases and 153 controls. Data were analyzed with conditional logistic regression with EGRET software. Odds ratios (ORs) were calculated for the relevant factors.
Single-variable analysis showed that schooling, history of exposure to PTB, history of Bacille Calmette-Guérin (BCG) vaccination and BCG vaccination scar all associated with the incidence of PTB, with ORs of 2.19, 2.03, 0.38 and 0.54, respectively, and P < 0.05. Multiple logistic regression analysis showed that BCG vaccination scar, history of exposure to PTB and schooling all entered the final regression model, with ORs of 0.36, 1.94 and 2.33, respectively.
It suggested that BCG vaccination could play a role in the prevention of TB in the servicemen, and history of exposure to PTB was a potential risk factor for TB as well.
研究军队服役人员肺结核(PTB)的危险因素,为其防控提供依据。
对军队服役人员进行1:2匹配的病例对照研究,病例86例,对照153例。采用EGRET软件进行条件logistic回归分析,计算相关因素的比值比(OR)。
单因素分析显示,受教育程度、接触肺结核病史、卡介苗(BCG)接种史及卡介苗接种瘢痕均与肺结核发病率有关,OR分别为2.19、2.03、0.38和0.54,P<0.05。多因素logistic回归分析显示,卡介苗接种瘢痕、接触肺结核病史及受教育程度均进入最终回归模型,OR分别为0.36、1.94和2.33。
提示卡介苗接种对军队服役人员预防结核病有一定作用,接触肺结核病史也是结核病的潜在危险因素。