Lilienthal B
Oral Surg Oral Med Oral Pathol. 1976 Nov;42(5):552-8. doi: 10.1016/0030-4220(76)90203-6.
A study of the cardiovascular responses to prilocaine hydrochloride (Citanest) given by intraosseous injection showed that there were no effects related to the absorption of this anesthetic. The presence of epinephrine in concentrations of 1:2000,000 was detected by its rapid absorption and stimulation of the heart rate. The injection of octapressin with prilocaine hydrochloride was usually accompanied by no heart rate or blood pressure changes. However, the heart rate decreased slightly in a few subjects, and this slower heart rate returned to preinjection values within 5 minutes.
一项关于骨内注射盐酸丙胺卡因(赛坦est)的心血管反应的研究表明,没有发现与这种麻醉剂吸收相关的影响。通过其快速吸收和对心率的刺激,检测到浓度为1:2000000的肾上腺素的存在。盐酸丙胺卡因与去氨加压素联合注射通常不会引起心率或血压变化。然而,少数受试者的心率略有下降,且这种较慢的心率在5分钟内恢复到注射前的值。