Kuna P
Strahlentherapie. 1976 Oct;152(4):377-84.
Administration of cystamine (20 mg base/kg s.c.) and 5-methoxytryptamine (10 mg base/kg i.m.) with 12 minutes delay to anesthetized rats induced the depression of whole cardiovascular system, hemoconcentration and great blood flow decrease in the radiosensitive tissues. Distributionof lowered cardiac output preferred the fractions to brain, heart, liver and lungs. Hemodynamic responses to protective combination may participate in its radioprotective action.
对麻醉大鼠皮下注射半胱胺（20毫克碱基/千克）和肌肉注射5-甲氧基色胺（10毫克碱基/千克），延迟12分钟，可导致整个心血管系统抑制、血液浓缩以及放射敏感组织的血流量大幅减少。心输出量降低的分布更倾向于大脑、心脏、肝脏和肺部等部位。对保护性组合的血流动力学反应可能参与其辐射防护作用。
