Vudiniabola S, Pirone C, Williamson J, Goss A N
Oral and Maxillofacial Surgery Unit, University of Adelaide.
Aust Dent J. 1999 Dec;44(4):243-7. doi: 10.1111/j.1834-7819.1999.tb00227.x.
Patients who have had their jaws irradiated as part of management of head and neck malignancy are at risk of osteoradionecrosis (ORN) following tooth extraction. Thirty-seven patients with a history of irradiation to the jaws were managed during a four year period. Twenty-nine patients received hyperbaric oxygen therapy (HBO) consisting of 20 treatments before surgery and ten treatments after. Only one (4 per cent) developed ORN. Seven patients who did not have HBO and one who did (15 per cent) developed ORN. The need for prophylactic treatment with HBO is discussed. It is recommended that prophylactic HBO is used prior to surgery for irradiated facial bones.
作为头颈部恶性肿瘤治疗一部分而接受颌骨放疗的患者,拔牙后有发生放射性骨坏死(ORN)的风险。在四年期间,对37例有颌骨放疗史的患者进行了治疗。29例患者接受了高压氧治疗(HBO),术前进行20次治疗,术后进行10次治疗。只有1例(4%)发生了ORN。7例未接受HBO治疗的患者和1例接受了HBO治疗的患者(15%)发生了ORN。讨论了预防性使用HBO治疗的必要性。建议在手术前对接受放疗的面骨使用预防性HBO。