Varela-Cives R, Bautista-Casasnovas A, Gude F, Cimadevila-Garcia A, Tojo R, Pombo M
Servicio de Cirugía Pediátrica, Unidad de Epidemiología Clínica, Hospital Clínico Universitario de Santiago, Santiago de Compostela, Spain.
J Urol. 2000 Mar;163(3):964-7.
We evaluated the role of a patent processus vaginalis for cryptorchidism as well as inguinal herniography as a predictor of the efficacy of human chorionic gonadotropin (HCG) treatment.
We studied 244 boys with unilateral and 66 with bilateral cryptorchidism. All patients underwent inguinal herniography and received HCG. Nonresponders to treatment subsequently underwent orchiopexy, when processus vaginalis status, testicular position and epididymal characteristics were assessed.
HCG was effective for 139 of 281 testes (49.5%) with an obliterated and 0 of 95 with a patent processus vaginalis on herniography. We further evaluated herniography in accordance with orchiopexy findings of persistent unilateral and bilateral cryptorchidism in 206 boys (237 testes) after HCG. Herniography findings of processus vaginalis morphology revealed a close correlation with that reported by the surgeon after orchiopexy (p<0.000005). The incidence of a patent processus vaginalis increased as testicular position became more caudal. The processus vaginalis was obliterated in all cases of anorchia. The incidence of more severe epididymal anomalies decreased as the testicular position became more caudal. Epididymal abnormalities were more common when the processus vaginalis was patent.
Pretreatment herniography assessment of processus vaginalis morphology is of prognostic value for predicting the efficacy of hormone treatment, the presence or absence of testes when they are nonpalpable and future fertility.
我们评估了鞘状突未闭在隐睾症中的作用以及腹股沟疝造影作为人绒毛膜促性腺激素(HCG)治疗疗效预测指标的价值。
我们研究了244名单侧隐睾症男孩和66名双侧隐睾症男孩。所有患者均接受了腹股沟疝造影并接受了HCG治疗。治疗无反应者随后接受睾丸固定术,同时评估鞘状突状态、睾丸位置和附睾特征。
在281个睾丸中,139个(49.5%)鞘状突已闭合的睾丸对HCG治疗有效,而在95个鞘状突未闭的睾丸中,对HCG治疗无反应者为0。我们根据HCG治疗后206名男孩(237个睾丸)持续性单侧和双侧隐睾症的睾丸固定术结果,进一步评估了腹股沟疝造影。鞘状突形态的腹股沟疝造影结果与睾丸固定术后外科医生报告的结果密切相关(p<0.000005)。随着睾丸位置变得更靠下,鞘状突未闭的发生率增加。在所有无睾症病例中,鞘状突均已闭合。随着睾丸位置变得更靠下,更严重的附睾异常发生率降低。当鞘状突未闭时,附睾异常更常见。
治疗前对鞘状突形态进行腹股沟疝造影评估,对于预测激素治疗疗效、不可触及睾丸的有无以及未来生育能力具有预后价值。