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丹麦肺癌的发病率:历史与现状

Incidence of lung cancer in Denmark: historical and actual status.

作者信息

Skuladottir H, Olsen J H, Hirsch F R

机构信息

Danish Cancer Society, Institute of Cancer Epidemiology, Copenhagen.

出版信息

Lung Cancer. 2000 Feb;27(2):107-18. doi: 10.1016/s0169-5002(99)00104-x.

Abstract

This is a registry-based analysis of 97,281 lung cancer patients diagnosed in Denmark during the period 1943-1994. The development of lung cancer incidence in Denmark in the study period is described and this information is used to predict the future trends in lung cancer in Denmark. Since 1960, lung cancer has been the most frequent type of cancer in Danish men, excluding skin cancer. The incidence in men reached its maximum in 1985, when it was 100 new cases per 100,000 inhabitants, whereafter the incidence began to level off and was 83 per 100,000 inhabitants in 1994. During the study period, the incidence of lung cancer in Danish women was somewhat lower than in men. The incidence in women has been steadily increasing since 1960 by approximately 20% per each 5-year period, and was 46 per 100,000 inhabitants in 1994. Adenocarcinoma is the most frequent histological subtype in women and the only subtype increasing in incidence in men. Taking the actual development into account, the incidence of lung cancer will continue to fall among men and rise among women, leading to a reversal of the classical gender ratio in about 15 years.

摘要

这是一项基于登记处数据的分析,研究对象为1943年至1994年期间在丹麦确诊的97281例肺癌患者。文中描述了研究期间丹麦肺癌发病率的变化情况,并利用这些信息预测丹麦未来肺癌的发展趋势。自1960年以来,肺癌一直是丹麦男性(不包括皮肤癌)中最常见的癌症类型。男性肺癌发病率在1985年达到峰值,每10万居民中有100例新发病例,此后发病率开始趋于平稳,1994年为每10万居民83例。在研究期间,丹麦女性肺癌发病率略低于男性。自1960年以来,女性肺癌发病率每5年稳步上升约20%,1994年为每10万居民46例。腺癌是女性中最常见的组织学亚型,也是男性中发病率唯一上升的亚型。考虑到实际发展情况,男性肺癌发病率将继续下降,女性肺癌发病率将继续上升,大约15年后经典的性别比例将发生逆转。

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