Skuladottir H, Hirsch F R, Olsen J H
Institut for Epidemiologisk Kraeftforskning, København.
Ugeskr Laeger. 1999 Nov 8;161(45):6179-84.
This study describes the development of lung cancer incidence in Denmark based on analysis of the Danish Cancer Registry database containing files on 97,281 lung cancer patients diagnosed in 1943-1994 in Denmark. Since 1960, lung cancer has been the most frequent type of cancer in Danish men, excluding skin cancer, the incidence reached its maximum in 1985, being 100 new cases per 100,000 inhabitants, but thereafter the incidence began to level off. During the study period, the incidence of lung cancer in Danish women was somewhat lower than in men, but increasing and was in 1994 46 per 100,000 inhabitants. Adenocarcinoma is the most frequent histological subtype in women and is the only histological subtype in men that is increasing in incidence. In conclusion, a decrease has been observed in the incidence of lung cancer among Danish males while the incidence of lung cancer in Danish women is increasing. Taking the actual development in incidence into account, the incidence of lung cancer will continue to fall among men and rise among women, leading to a reversal of the classical gender ratio in about 15 years.
本研究基于对丹麦癌症登记数据库的分析，描述了丹麦肺癌发病率的发展情况。该数据库包含1943年至1994年在丹麦诊断出的97281例肺癌患者的档案。自1960年以来，肺癌一直是丹麦男性（不包括皮肤癌）中最常见的癌症类型，发病率在1985年达到最高，为每10万居民中有100例新发病例，但此后发病率开始趋于平稳。在研究期间，丹麦女性肺癌的发病率略低于男性，但呈上升趋势，1994年为每10万居民中有46例。腺癌是女性中最常见的组织学亚型，也是男性中发病率唯一呈上升趋势的组织学亚型。总之，丹麦男性肺癌发病率有所下降，而丹麦女性肺癌发病率在上升。考虑到发病率的实际发展情况，男性肺癌发病率将继续下降，女性肺癌发病率将继续上升，大约15年后经典的性别比例将发生逆转。
