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碘化钾与沃尔夫-柴可夫效应：对皮肤科医生的相关性。

Potassium iodide and the wolff-chaikoff effect: relevance for the dermatologist.

作者信息

Heymann W R

机构信息

Division of Dermatology, UMDNJ-Robert Wood Johnson School of Medicine, Marlton, NJ 08053

出版信息

J Am Acad Dermatol. 2000 Mar;42(3):490-2. doi: 10.1016/s0190-9622(00)90224-x.

DOI:10.1016/s0190-9622(00)90224-x
PMID:10688722
Abstract

The inhibition of organic binding of iodide in the thyroid gland by excess iodide, resulting in the cessation of thyroid hormone synthesis, is known as the Wolff-Chaikoff effect. This review explores the nature of the Wolff-Chaikoff effect, both in terms of its potential mechanisms and its relevance to dermatologists who use potassium iodide as a therapeutic agent.

摘要

过量碘化物对甲状腺中碘化物有机结合的抑制作用，导致甲状腺激素合成停止，这被称为沃尔夫-柴可夫效应。本综述探讨了沃尔夫-柴可夫效应的本质，包括其潜在机制以及与将碘化钾用作治疗剂的皮肤科医生的相关性。

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引用本文的文献

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Ann Med. 2025 Dec;57(1):2488180. doi: 10.1080/07853890.2025.2488180. Epub 2025 Sep 18.
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Potassium Iodide in Dermatology- Recent Advances in Mechanism of Action, Preparation, Uses and Adverse Effects.皮肤科中的碘化钾——作用机制、制剂、用途及不良反应的最新进展
Indian J Dermatol. 2025 May-Jun;70(3):169. doi: 10.4103/ijd.ijd_508_24. Epub 2025 May 8.
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Potassium Iodide and Monitoring of Thyroid Function gap - From a Dermatologist's Perspective.
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An Bras Dermatol. 2013 May-Jun;88(3):396-402. doi: 10.1590/abd1806-4841.20132377.