al Drees K, al Zaben A, al Amir A, Abdulla A
Department of Paediatrics, King Fahad National Guard Hospital, Riyadh, Saudi Arabia.
Ann Trop Paediatr. 1999 Jun;19(2):215-7. doi: 10.1080/02724939992563.
We report a case of benign recurrent intrahepatic cholestasis (BRIC) in an 11-year-old Saudi girl who developed three episodes of pruritus and jaundice at the ages of 4, 8, and 9 years. These episodes were almost stereotypic and lasted 5-8 weeks. Although she had elevated liver enzymes and serum bile acids in her blood during the attacks, they returned to normal between attacks. Thorough investigation excluded other causes of liver disease and her recurrent attacks were shortened by cholestyramine therapy. A diagnosis of BRIC should be kept in mind in patients with cholestasis.
我们报告一例11岁沙特女孩的良性复发性肝内胆汁淤积症（BRIC），该女孩在4岁、8岁和9岁时出现了三次瘙痒和黄疸发作。这些发作几乎是刻板的，持续5至8周。尽管在发作期间她血液中的肝酶和血清胆汁酸升高，但在发作间歇期恢复正常。全面检查排除了其他肝病原因，考来烯胺治疗缩短了她的复发发作时间。对于胆汁淤积患者应考虑BRIC的诊断。
