法国遗传学流派：从生理遗传学和群体遗传学到调控分子遗传学。

The French school of genetics: from physiological and population genetics to regulatory molecular genetics.

作者信息

Burian R M, Gayon J

机构信息

Department of Philosophy, Virginia Polytechnic Institute and State University, Blacksburg 24061-0126, USA.

出版信息

Annu Rev Genet. 1999;33:313-49. doi: 10.1146/annurev.genet.33.1.313.

DOI:10.1146/annurev.genet.33.1.313

PMID:10690411

Abstract

French genetics had unusual beginnings. There are clear indications that the French biological establishment resisted Mendelian genetics strenuously from about 1910 to 1940. From about 1930 to 1950 several unconventional research programs with a strongly physiological orientation paved the way for the full entrance of French biology into genetics after World War II. This review examines some salient features of this history to clarify the strengths, weaknesses, and distinctive features of French genetics until about 1965. We suggest that after that data French genetics slowly merged into the international mainstream as genetics has become a largely molecular discipline.

摘要

法国遗传学有着不同寻常的开端。有明确迹象表明，从大约1910年到1940年，法国生物学界强烈抵制孟德尔遗传学。从大约1930年到1950年，几个具有强烈生理学倾向的非传统研究项目为二战后法国生物学全面进入遗传学领域铺平了道路。这篇综述考察了这段历史的一些显著特征，以阐明直到大约1965年法国遗传学的优势、劣势和独特之处。我们认为，在那之后，随着遗传学在很大程度上已成为一门分子学科，法国遗传学逐渐融入国际主流。