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[黄热病在西非的再度出现:历史教训,呼吁实施防控计划]

[Reemergence of yellow fever in West Africa: lessons from the past, advocacy for a control program].

作者信息

Moreau J P, Girault G, Dramé I, Perraut R

机构信息

Unité du vaccin fièvre jaune, Institut Pasteur de Dakar, Sénégal.

出版信息

Bull Soc Pathol Exot. 1999 Dec;92(5):333-6.

PMID:10690471
Abstract

In French speaking West Africa, yellow fever vaccine became compulsory in 1941 for the entire African and European population. From 1941 to 1960, 146 million doses were distributed and the number of yellow fever cases declined sharply. No case was reported from 1954 to 1960. As a result of an interruption in systematic immunization after 1960, ten major epidemics broke out in West Africa between 1965 and 1995 (over 200,000 cases and 40,000 deaths). In 1967, the WHO programme for eradication of smallpox was initiated and it mobilized WHO's energy and finances. The expanded programme of immunization (EPI) was initiated in 1977 but it did not include the yellow fever vaccine. In 1978, Primary Health Care advocated an immunization strategy through fixed health facilities. In 1986, to amend this strategy, WHO recommended accelerating EPI progress and instituting National Immunization Days (NIDs). In 1990, a recommendation was made to include the yellow fever vaccine in the EPI. In 1997, the target of global poliomyelitis eradication by the year 2000 reinforced the NID programme and led to the use of mobile teams. At a time when a measles eradication programme is going to take over from the poliomyelitis programme, we must firmly advocate not omitting the yellow fever vaccine as was the case in 1977. Indeed, in yellow fever endemic areas, WHO recommends a simultaneous association of yellow fever and measles vaccines for nine month-old infants. This opportunity must be seized to initiate a yellow fever control programme.

摘要

在说法语的西非地区,1941年黄热病疫苗对所有非洲人和欧洲人强制接种。1941年至1960年期间,共分发了1.46亿剂疫苗,黄热病病例数急剧下降。1954年至1960年期间未报告任何病例。1960年后由于系统免疫接种中断,1965年至1995年期间西非爆发了十次重大疫情(超过20万病例和4万例死亡)。1967年,世卫组织发起了根除天花计划,该计划调动了世卫组织的精力和资金。扩大免疫规划(EPI)于1977年启动,但未包括黄热病疫苗。1978年,初级卫生保健倡导通过固定卫生设施进行免疫接种策略。1986年,为修订这一策略,世卫组织建议加快扩大免疫规划进程并设立全国免疫日(NIDs)。1990年,建议将黄热病疫苗纳入扩大免疫规划。1997年,到2000年全球根除脊髓灰质炎的目标加强了全国免疫日计划,并导致使用流动团队。在麻疹根除计划即将取代脊髓灰质炎计划之际,我们必须坚决主张不要像1977年那样遗漏黄热病疫苗。事实上,在黄热病流行地区,世卫组织建议为9个月大的婴儿同时接种黄热病和麻疹疫苗。必须抓住这个机会启动黄热病控制计划。

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