Harrison J E, Preston S, Blunt S B
CeNeS Ltd, Histon, Cambridge, UK.
Age Ageing. 2000 Jan;29(1):41-5. doi: 10.1093/ageing/29.1.41.
The 39-item Parkinson's disease questionnaire (PDQ-39) is more sensitive to functional change than other measures of health and disability.
To determine the ability of this scale to change over time and the concurrent validity of some of its subscales.
We assessed a cohort of 67 Parkinson's patients for 18 months, using the PDQ-39, the GHQ-28 general health questionnaire and the Office of Population and Census Surveys disability instrument.
The Office of Population and Census Surveys disability instrument and GHQ-28 recorded no significant change, but the PDQ-39 showed marked changes in levels of functioning. We also analysed changes on the PDQ-39 subscales as well as concurrent validity data for several subscales. This showed concurrent validity with the Beck depression and anxiety inventories, the Barthel index and the Royal Postgraduate Medical School severity scale. There was a high level of concurrent validity for all comparisons except for the Barthel index.
The PDQ-39 is a sensitive tool for monitoring change in patients with Parkinson's disease. It has high levels of concurrent validity with established measures of mood and motor function.
39项帕金森病问卷（PDQ - 39）在反映功能变化方面比其他健康和残疾测量方法更为敏感。
确定该量表随时间变化的能力及其部分分量表的同时效度。
我们使用PDQ - 39、GHQ - 28一般健康问卷和人口普查残疾评定工具，对67名帕金森病患者进行了为期18个月的评估。
人口普查残疾评定工具和GHQ - 28未显示出显著变化，但PDQ - 39显示出功能水平的显著变化。我们还分析了PDQ - 39各分量表的变化以及几个分量表的同时效度数据。结果表明，它与贝克抑郁和焦虑量表、巴氏指数以及皇家研究生医学院严重程度量表具有同时效度。除巴氏指数外，所有比较的同时效度水平都很高。
PDQ - 39是监测帕金森病患者变化的敏感工具。它与既定的情绪和运动功能测量方法具有较高的同时效度。
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