Suratos Cezar Thomas R, Saranza Gerard Raimon M, Sumalapao Derick Erl P, Jamora Roland Dominic G
Department of Neurosciences, College of Medicine - Philippine General Hospital, University of the Philippines Manila, Taft Avenue, Manila 1000, Philippines.
Department of Biology, College of Science, De La Salle University, Manila 1004, Philippines; Department of Medical Microbiology, College of Public Health, University of the Philippines Manila, Manila, 1000, Philippines.
J Clin Neurosci. 2018 Aug;54:156-160. doi: 10.1016/j.jocn.2018.06.013. Epub 2018 Jun 12.
The 39-item Parkinson's Disease Quality of Life Questionnaire (PDQ-39) is the most widely used self-administered questionnaire assessing the quality of life of Parkinson's disease (PD) patients. We translated the PDQ-39 into the Filipino language as the Philippine-PDQ-39 (P-PDQ-39) and used it to assess the quality of life of Filipino patients with PD. The original PDQ-39 was translated into Filipino using forward and backward translation by independent bilingual translators and used among 100 consecutively sampled PD patients. Baseline demographic data, disease duration and levodopa equivalent dose were collected. Internal consistency was measured using Chronbach's α. The following rating scales and questionnaires were correlated with P-PDQ-39 through Pearson's correlation coefficient to assess construct validity: modified Hoehn & Yahr Stage, Hospital Anxiety and Depression Scale-Pilipino (HADS-P), Unified Parkinson's Disease Rating Scale (UPDRS) Parts I-III, and Non-motor symptom Assessment Scale for Parkinson's Disease (NMSS). The mobility and activities of daily living domains of the P-PDQ-39 were well correlated with the Hoehn & Yahr stage of the patients and the UPDRS II and III scores emphasizing the value of motor symptoms in quality of life. Non motor symptoms in PD were also important determinants of quality of life as demonstrated in the correlation of HADS-P and NMSS Total scores with the P-PDQ 39 domains. The P-PDQ-39 is a valid assessment tool for assessing the quality of life of Filipino-speaking PD patients.
39项帕金森病生活质量问卷（PDQ - 39）是评估帕金森病（PD）患者生活质量时使用最广泛的自填式问卷。我们将PDQ - 39翻译成菲律宾语，即菲律宾 - PDQ - 39（P - PDQ - 39），并用它来评估菲律宾PD患者的生活质量。最初的PDQ - 39由独立的双语翻译人员通过正向和反向翻译翻译成菲律宾语，并在100例连续抽样的PD患者中使用。收集了基线人口统计学数据、病程和左旋多巴等效剂量。使用克朗巴赫α系数测量内部一致性。通过皮尔逊相关系数将以下评定量表和问卷与P - PDQ - 39相关联，以评估结构效度：改良的Hoehn & Yahr分期、菲律宾医院焦虑抑郁量表（HADS - P）、统一帕金森病评定量表（UPDRS）第一至三部分，以及帕金森病非运动症状评估量表（NMSS）。P - PDQ - 39的移动性和日常生活领域与患者的Hoehn & Yahr分期以及UPDRS II和III评分密切相关，强调了运动症状在生活质量中的价值。PD中的非运动症状也是生活质量的重要决定因素，这在HADS - P和NMSS总分与P - PDQ 39各领域的相关性中得到了体现。P - PDQ - 39是评估说菲律宾语的PD患者生活质量的有效评估工具。
