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椎板切除术与经皮电极置入用于脊髓刺激的比较。

Laminectomy versus percutaneous electrode placement for spinal cord stimulation.

作者信息

Villavicencio A T, Leveque J C, Rubin L, Bulsara K, Gorecki J P

机构信息

Division of Neurosurgery, Duke University Medical Center, Durham, North Carolina 27712, USA.

出版信息

Neurosurgery. 2000 Feb;46(2):399-405; discussion 405-6. doi: 10.1097/00006123-200002000-00025.

DOI:10.1097/00006123-200002000-00025
PMID:10690729
Abstract

OBJECTIVE

The purpose of this study was to compare the long-term effectiveness of spinal cord stimulation using laminectomy-style electrodes versus that using percutaneously implanted electrodes.

METHODS

Forty-one patients underwent an initial trial period of spinal cord stimulation with temporary electrodes at Duke Medical Center between December 1992 and January 1998. A permanent system was implanted if trial stimulation reduced the patient's pain by more than 50%. Median long-term follow-up after permanent electrode placement was 34 months (range, 6-66 mo). Severity of pain was determined postoperatively by a disinterested third party using a visual analog scale and a modified outcome scale.

RESULTS

Twenty-seven (66%) of the 41 patients participating in the trial had permanent electrodes placed. Visual analog scores decreased an average of 4.6 among patients in whom electrodes were placed via laminectomy in the thoracic region (two-tailed t test, P < 0.0001). Patients who underwent percutaneous placement of thoracic electrodes had an average decrease of 3.1 in their visual analog scores (two-tailed t test, P < 0.001). Electrodes placed through laminectomy furnished significantly greater long-term pain relief than did those placed percutaneously, as measured by a four-tier outcome grading scale (P = 0.02).

CONCLUSION

Spinal cord stimulation is an effective treatment for chronic pain in the lower back and lower extremities that is refractory to conservative therapy. Electrodes placed via laminectomy in the thoracic region appear to be associated with significantly better long-term effectiveness than are electrodes placed percutaneously.

摘要

目的

本研究旨在比较采用椎板切除术式电极与经皮植入电极进行脊髓刺激的长期效果。

方法

1992年12月至1998年1月期间,41例患者在杜克医学中心接受了临时电极脊髓刺激初始试验期。如果试验刺激使患者疼痛减轻超过50%,则植入永久系统。永久电极植入后的中位长期随访时间为34个月(范围6 - 66个月)。术后由无利害关系的第三方使用视觉模拟量表和改良结果量表确定疼痛严重程度。

结果

参与试验的41例患者中有27例(66%)植入了永久电极。在通过椎板切除术在胸段放置电极的患者中,视觉模拟评分平均下降4.6(双侧t检验,P < 0.0001)。经皮在胸段放置电极的患者视觉模拟评分平均下降3.1(双侧t检验,P < 0.001)。通过椎板切除术放置的电极在长期疼痛缓解方面比经皮放置的电极显著更好,这通过四级结果分级量表测量(P = 0.02)。

结论

脊髓刺激是治疗对保守治疗无效的下背部和下肢慢性疼痛的有效方法。在胸段通过椎板切除术放置的电极似乎比经皮放置的电极具有显著更好的长期效果。

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