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复杂性青光眼序贯性引流管分流术的治疗效果

Outcomes of sequential tube shunts in complicated glaucoma.

作者信息

Burgoyne J K, WuDunn D, Lakhani V, Cantor L B

机构信息

Department of Ophthalmology, Indiana University, Indianapolis 46202, USA.

出版信息

Ophthalmology. 2000 Feb;107(2):309-14. doi: 10.1016/s0161-6420(99)00039-1.

Abstract

OBJECTIVE

To evaluate intraocular pressure (IOP) control, change in visual acuity, and complications in eyes that have undergone a second glaucoma tube shunt procedure.

DESIGN

Retrospective, noncomparative case series.

PARTICIPANTS

Twenty-two eyes of 22 patients that have undergone sequential tube implants for management of glaucoma.

METHODS

Parameters analyzed included IOP, visual acuity, and number of hypotensive agent before each shunt procedure and at last follow-up visit. The overall IOP lowering effect attributable to each tube shunt was calculated. Any ocular complications after the second tube shunt were recorded. Success was defined as an IOP between 6 and 21 mm Hg and a 20% reduction in IOP from the second tube shunt procedure. Qualified successes met one of these two requirements at the last follow-up visit. Total failures did not meet any of the above criteria, required additional surgical intervention to lower IOP, or both.

MAIN OUTCOME MEASURES

Intraocular pressure control, visual acuity preservation, and complications.

RESULTS

At the last follow-up visit, the average percent reduction in IOP from both tube shunt procedures was 42+/-21%. The average percent IOP reduction from the second tube shunt was 33+/-17%. Eleven (50%) patients met the criteria for success, 8 (36.4%) patients were qualified successes, and 3 (13.6%) were failures. The median number of hypotensive agents decreased from two to one. Ten patients experienced new or worse pseudophakic bullous keratopathy after the second tube shunt, six of whom underwent penetrating keratoplasty. Thirteen (59%) patients maintained visual acuity within one line of their second tube shunt pre-operative Snellen visual acuity. Seven (32%) patients lost more than 2 lines, and one patient lost light perception.

CONCLUSIONS

Although corneal morbidity is a common complication, a second tube shunt does not cause higher-than-expected rates of other complications associated with tube shunt surgery. Eyes that undergo a second tube shunt procedure can achieve pressure control, require fewer hypotensive agents, and may maintain stable visual acuity.

摘要

目的

评估接受二次青光眼引流管分流手术的眼睛的眼压控制情况、视力变化及并发症。

设计

回顾性、非对照病例系列研究。

研究对象

22例患者的22只眼睛,这些患者接受了序贯性引流管植入术以治疗青光眼。

方法

分析的参数包括每次分流手术前及最后一次随访时的眼压、视力及降压药物使用数量。计算每次引流管分流术的总体眼压降低效果。记录二次引流管分流术后的任何眼部并发症。成功定义为眼压在6至21mmHg之间且眼压较二次引流管分流手术时降低20%。合格成功在最后一次随访时满足上述两项要求之一。完全失败未达到上述任何标准,需要额外的手术干预来降低眼压,或两者皆需。

主要观察指标

眼压控制、视力保留及并发症。

结果

在最后一次随访时,两次引流管分流术使眼压平均降低42±21%。二次引流管分流术使眼压平均降低33±17%。11例(50%)患者达到成功标准,8例(36.4%)患者为合格成功,3例(13.6%)为失败。降压药物的中位数从两种减少至一种。10例患者在二次引流管分流术后出现新的或更严重的人工晶状体大泡性角膜病变,其中6例接受了穿透性角膜移植术。13例(59%)患者的视力保持在二次引流管分流术前Snellen视力的一行以内。7例(32%)患者视力下降超过2行,1例患者丧失光感。

结论

尽管角膜病变是常见并发症,但二次引流管分流术不会导致高于预期的与引流管分流手术相关的其他并发症发生率。接受二次引流管分流手术的眼睛可实现眼压控制,减少降压药物使用,且可能维持稳定的视力。

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