巴西利什曼原虫前鞭毛体和无鞭毛体与宿主巨噬细胞的相互作用方式不同。
Leishmania braziliensis promastigotes and amastigotes interact differently with host macrophages.
作者信息
Strauss M, Tejero F, Argüello C
机构信息
Department of Experimental Cardiology, Institute of Tropical Medicine, Faculty of Medicine, Central University of Venezuela, Caracas, Venezuela.
出版信息
J Submicrosc Cytol Pathol. 1993 Jul;25(3):449-54.
In vitro and in vivo ultrastructral studies reveal that the parasite entrance into the macrophage occurs by phagocytosis. The early stage of phagocytosis exhibited different ultrastructural characteristics in both forms of the parasite. Long and prominent projections from peritoneal exudate macrophages made focal contacts with the promastigote surface. The amastigotes, in turn, laid on cup-shaped extensions of the macrophage membrane. Later stages of the phagocytosis are characterized by progressive and complete engulfment of both promastigotes and amastigotes.
体外和体内超微结构研究表明，寄生虫通过吞噬作用进入巨噬细胞。吞噬作用的早期阶段在两种寄生虫形态中表现出不同的超微结构特征。腹膜渗出巨噬细胞伸出的长而突出的突起与前鞭毛体表面形成局部接触。反过来，无鞭毛体则位于巨噬细胞膜的杯状延伸部分上。吞噬作用的后期阶段以对前鞭毛体和无鞭毛体的逐步和完全吞噬为特征。
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