Giner J L, Berkowitz J D, Andersson T
Department of Chemistry, SUNY-ESF, Syracuse, New York 13210, USA.
J Nat Prod. 2000 Feb;63(2):267-9. doi: 10.1021/np990081g.
The less polar fractions of the latex of Euphorbia peplus were found to contain obtusifoliol, cycloartenol, 24-methylenecycloartanol, lanosterol, and 24-methylenelanosterol in the free and esterified triterpene alcohol fractions; 9-cis-tricosene as the major component of the hydrocarbon fraction; and a new acyclic triterpene alcohol named peplusol (1). The structure of 1 was determined as the R-isomer of (all-E)-2-(5,9-dimethyl-1-methylene-4,8-decadienyl)-5,9, 13-trimethyl-4,8,12-tetradecatrien-1-ol by spectral and chemical methods.
大戟乳汁中极性较小的部分在游离和酯化的三萜醇部分中含有 obtusifoliol、环阿屯醇、24-亚甲基环阿屯醇、羊毛甾醇和 24-亚甲基羊毛甾醇；9-顺式二十三碳烯是烃类部分的主要成分；还有一种名为peplusol(1)的新型无环三萜醇。通过光谱和化学方法确定1的结构为(all-E)-2-(5,9-二甲基-1-亚甲基-4,8-癸二烯基)-5,9,13-三甲基-4,8,12-十四碳三烯-1-醇的R-异构体。
