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注意力缺陷多动障碍:可能的病因及治疗方法

Attention deficit hyperactivity disorder: possible causes and treatment.

作者信息

Gordon N

出版信息

Int J Clin Pract. 1999 Oct-Nov;53(7):524-8.

Abstract

The possible causes of attention deficit hyperactivity disorder are considered, and the drugs that may be of benefit in treating it. Accurate diagnosis is essential for effective management. This includes the syndrome itself and associated conditions. Theories of causation are discussed. These involve the anatomical substrate but, equally importantly, the role of neurotransmitters; and the use of tests such as positron emission tomography will undoubtedly increase understanding. Genetic factors also play a part. Options for treatment are considered. Evidence supports the effectiveness of stimulant drugs, such as methylphenidate. Among the justifications for such treatment are the excessive strains placed on family relationships by the condition, and the disruption of the child's schooling. It must be carefully planned, and a constant watch kept for adverse effects. These can include difficulty in sleeping, poor appetite, loss of weight and tics. Drugs alone, however, are unlikely to help, and attention must first be given to the situation at home and at school, and how this can be improved. Treatment is often successful, and it can be a rewarding condition to treat.

摘要

文中探讨了注意力缺陷多动障碍的可能成因以及可能有助于治疗该疾病的药物。准确诊断对于有效管理至关重要。这包括该综合征本身及相关病症。文中讨论了病因理论。这些理论涉及解剖学基础,但同样重要的是神经递质的作用;正电子发射断层扫描等检测手段的应用无疑会增进我们的理解。遗传因素也起到一定作用。文中还考虑了治疗方案。有证据支持兴奋剂药物(如哌甲酯)的有效性。进行此类治疗的理由包括该病症给家庭关系带来的过度压力以及对孩子学业的干扰。治疗必须精心规划,并持续留意不良反应。这些不良反应可能包括睡眠困难、食欲不振、体重减轻和抽搐。然而,仅靠药物治疗可能并无帮助,必须首先关注家庭和学校环境,并考虑如何加以改善。治疗通常会取得成功,而且这是一种值得治疗的病症。

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