[雄性C57Bl/6J和CBA/Lac小鼠遗传性诱导焦虑表现的特征]

[The characteristics of the manifestation of hereditarily induced anxiety in male C57Bl/6J and CBA/Lac mice].

作者信息

Avgustinovich D F, Lipina T V, Bondar' N P, Kudriavtseva N N

机构信息

Institute of Cytology and Genetics, Russian Academy of Sciences, Siberian Branch, Novosibirsk.

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1999 Nov-Dec;49(6):1008-17.

PMID:10693281

Abstract

Behavior of male mice of C57Bl/6J and CBA/Lac strains was tested in the elevated plus-maze and open field in order to estimate state anxiety in novel conditions. The cube and partition tests were used to reveal trait anxiety in the familiar conditions of the home cage. It is concluded that genetically defined state anxiety is more pronounced in CBA/Lac mice and trait anxiety in C57Bl/6J strain.

摘要

为了评估在新环境下的状态焦虑，对C57Bl/6J和CBA/Lac品系的雄性小鼠在高架十字迷宫和旷场中进行了行为测试。使用方块和分隔测试来揭示在熟悉的饲养笼环境中的特质焦虑。得出的结论是，基因定义的状态焦虑在CBA/Lac小鼠中更明显，而特质焦虑在C57Bl/6J品系中更明显。