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铒:钇铝石榴石激光屈光性角膜切除术的局限性。

Limitations of erbium:YAG laser photorefractive keratectomy.

作者信息

Mrochen M, Semshichen V, Funk R H, Seiler T

机构信息

University of Dresden, Department of Ophthalmology, Germany.

出版信息

J Refract Surg. 2000 Jan-Feb;16(1):51-9. doi: 10.3928/1081-597X-20000101-07.

Abstract

PURPOSE

The erbium:YAG laser (lambda = 2.94 microm) has been considered promising as an alternative to the ArF excimer laser in photorefractive keratectomy (PRK). However, corneal application of this mid-infrared solid state laser is still plagued with various disadvantages compared to that of the ArF excimer laser (lambda = 193 nm). We discuss the limitations of PRK with the erbium:YAG laser.

METHODS

Measurements of ablation threshold, ablation efficiency, and thermal damage were done to compare the process of erbium:YAG laser photoevaporization to the ArF excimer laser. PRK procedures were performed on fresh enucleated pig corneas to investigate the morphology and surface roughness of the cornea after scanning-spot and fundamental mode photoablation. Surface roughness was measured by using a tactile surface reprofiling system.

RESULTS

The ablation threshold and the ablation efficiencies for the erbium:YAG laser are significantly higher compared to the ArF excimer laser. Collateral thermal damage decreases with a reduction of laser pulse duration to a minimum of approximately 5 microm. Scanning electron microscopy and surface roughness measurements of the corneal surface after erbium:YAG laser treatment demonstrated higher surface roughness compared to ArF excimer laser treatments.

CONCLUSIONS

The erbium:YAG laser is not at present an alternative to the ArF excimer laser for photorefractive keratectomy.

摘要

目的

铒:钇铝石榴石激光(波长=2.94微米)被认为有望在准分子激光原位角膜磨镶术(PRK)中替代氟化氩准分子激光。然而,与氟化氩准分子激光(波长=193纳米)相比,这种中红外固态激光在角膜上的应用仍存在各种缺点。我们讨论了铒:钇铝石榴石激光用于PRK的局限性。

方法

进行了消融阈值、消融效率和热损伤的测量,以比较铒:钇铝石榴石激光光蒸发过程与氟化氩准分子激光的过程。在新鲜摘除的猪角膜上进行PRK手术,以研究扫描光斑和基模光消融后角膜的形态和表面粗糙度。使用触觉表面轮廓测量系统测量表面粗糙度。

结果

与氟化氩准分子激光相比,铒:钇铝石榴石激光的消融阈值和消融效率显著更高。随着激光脉冲持续时间减少至约5微米的最小值,附带热损伤降低。铒:钇铝石榴石激光治疗后角膜表面的扫描电子显微镜和表面粗糙度测量显示,与氟化氩准分子激光治疗相比,表面粗糙度更高。

结论

目前,铒:钇铝石榴石激光在准分子激光原位角膜磨镶术中不能替代氟化氩准分子激光。

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