Stylianos S
Babies and Children's Hospital, New York, NY 10032, USA.
J Pediatr Surg. 2000 Feb;35(2):164-7; discussion 167-9. doi: 10.1016/s0022-3468(00)90003-4.
This study is intended to resolve the disparity and reach consensus on issues regarding the treatment of children with isolated spleen or liver injuries. To maximize patient safety and assure efficient, cost-effective utilization of resources, it was essential to determine current practice.
Data from the case records of 856 children with isolated spleen or liver injury treated at 32 pediatric surgical centers from July 1995 to June 1997 were collected. The severity of injury was classified by computed tomography (CT) grade and the data analyzed for intensive care unit (ICU) stay, length of hospital stay, transfusion requirement, need for operation, pre- and postdischarge imaging, and restriction of physical activity. Patients with grade V injuries (2.8%) were excluded leaving 832 patients for detailed review. These data and available literature were analyzed for consensus by the 1998 APSA Trauma Committee.
Resource utilization increased with injury severity (see Table 2). Based on the data analysis, literature search, and consensus conference, the authors propose guidelines (see Table 3) for the safe and optimal utilization of resources in routine cases. It is important to emphasize that no recommendation falls outside the 25th percentile of current practice at participating centers.
Diversity of treatment, with attendant variation in resource utilization in children with isolated spleen and liver injury of comparable severity is confirmed. This analysis has stimulated a prospective outcomes study with the objective of validating the evidence-based guidelines proposed. This evidence-based study design can bring order and conformity to patient management resulting in optimal utilization of resources while maximizing patient safety.
本研究旨在解决关于单纯脾或肝损伤儿童治疗问题上的差异并达成共识。为了最大限度地提高患者安全性并确保资源的高效、经济有效利用,确定当前的治疗实践至关重要。
收集了1995年7月至1997年6月期间在32个儿科手术中心接受治疗的856例单纯脾或肝损伤儿童的病例记录数据。损伤严重程度通过计算机断层扫描(CT)分级,对重症监护病房(ICU)住院时间、住院时长、输血需求、手术需求、出院前后影像学检查以及体力活动限制等数据进行分析。V级损伤患者(2.8%)被排除,剩余832例患者进行详细审查。1998年美国小儿外科协会创伤委员会对这些数据和现有文献进行分析以达成共识。
资源利用随着损伤严重程度增加(见表2)。基于数据分析、文献检索和共识会议,作者提出了常规病例中资源安全和优化利用的指南(见表3)。需要强调的是,没有任何建议超出参与中心当前治疗实践的第25百分位数。
证实了在具有相当严重程度的单纯脾和肝损伤儿童中,治疗存在多样性以及随之而来的资源利用差异。该分析促使开展一项前瞻性结局研究,目的是验证所提出的循证指南。这种循证研究设计可以使患者管理有序且一致,从而在最大限度提高患者安全性的同时实现资源的优化利用。