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马萨诸塞州男性老龄化研究中勃起功能障碍状态的一个新替代变量。

A new surrogate variable for erectile dysfunction status in the Massachusetts male aging study.

作者信息

Kleinman K P, Feldman H A, Johannes C B, Derby C A, McKinlay J B

机构信息

New England Research Institutes Inc., Watertown, MA 02472, USA.

出版信息

J Clin Epidemiol. 2000 Jan;53(1):71-8. doi: 10.1016/s0895-4356(99)00150-x.

Abstract

Erectile dysfunction (ED) is the subject of a vast clinical literature, but little information has been gathered from random samples of the general public. The Massachusetts Male Aging Study (MMAS) addressed this important aspect of men's health. The MMAS was conducted in two waves, with baseline data collection in 1987-1989 and follow-up in 1995-1997. Subsequent to the baseline MMAS survey, a consensus developed that subjective measures are optimal for defining ED. Unfortunately, the baseline questionnaire did not ask subjects directly about their erectile functioning. Thus, we previously assigned the MMAS subjects a degree of impotence at baseline using a series of related questions, employing a discriminant formula constructed from a separate sample of urology clinic patients. At follow-up the men classified themselves directly in addition to answering the original series of related questions. In the present article, we report the results of a new discriminant function, based on the MMAS men at follow-up. We also compare the two methods and discuss our reasons for preferring the internally calibrated method.

摘要

勃起功能障碍(ED)是大量临床文献的主题,但从普通公众随机样本中收集到的信息很少。马萨诸塞男性衰老研究(MMAS)探讨了男性健康的这一重要方面。MMAS分两波进行,1987 - 1989年收集基线数据,1995 - 1997年进行随访。在MMAS基线调查之后,人们形成了一种共识,即主观测量方法最适合定义ED。不幸的是,基线调查问卷没有直接询问受试者的勃起功能。因此,我们之前使用一系列相关问题,通过一个由泌尿外科门诊患者单独样本构建的判别公式,为MMAS受试者在基线时确定了一定程度的阳痿情况。在随访时,除了回答原来的一系列相关问题外,男性还直接对自己进行了分类。在本文中,我们报告基于MMAS随访男性的新判别函数的结果。我们还比较了这两种方法,并讨论了我们更倾向于内部校准方法的原因。

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