Rizvi N, Rao N A, Hussain M
Department of Chest Medicine, Jinnah Postgraduate Medical Centre, Karachi, Pakistan.
Int J Tuberc Lung Dis. 2000 Feb;4(2):147-51.
To determine the yield of acid-fast bacilli (AFB) in gastric lavage and bronchial washing in adult patients clinically and radiologically suspected of pulmonary tuberculosis but who cannot produce sputum.
Selected adult patients were admitted to the ward; gastric lavage was done for 3 consecutive days after an overnight fast followed by bronchial wash. Specimens were immediately sent to laboratory for AFB direct smear and culture.
The yield of AFB in gastric lavage on direct smear was 16/20 (80%) and 12/20 (60%) in the first and second samples, respectively. When combined, 18/20 (90%) were direct smear positive, while the third sample did not increase the yield. The yield of AFB culture in gastric lavage was 6/20 (30%) in both the first and second samples, while the combined results of the first and second samples were 8/20 (40%). The third sample did not increase the yield. In bronchial wash, AFB direct smear was positive in 18/20 (90%), while culture was positive in 14/20 (70%).
Gastric lavage and bronchial washing are useful methods for the diagnosis of pulmonary tuberculosis in patients who cannot produce sputum. Two gastric lavage specimens are adequate. On comparison, bronchial wash is superior to gastric lavage in culture, but their yield on direct smear is equal.
确定临床上和影像学上怀疑患有肺结核但无法咳痰的成年患者胃灌洗和支气管灌洗中抗酸杆菌(AFB)的检出率。
选择成年患者入院;禁食过夜后连续3天进行胃灌洗,随后进行支气管灌洗。标本立即送实验室进行AFB直接涂片和培养。
胃灌洗直接涂片AFB检出率在第一份标本中为16/20(80%),第二份标本中为12/20(60%)。两者合并后,18/20(90%)直接涂片阳性,而第三份标本未提高检出率。胃灌洗AFB培养在第一份和第二份标本中均为6/20(30%),第一份和第二份标本合并结果为8/20(40%)。第三份标本未提高检出率。支气管灌洗中,AFB直接涂片18/20(90%)阳性,培养14/20(70%)阳性。
胃灌洗和支气管灌洗是诊断无法咳痰患者肺结核的有用方法。两份胃灌洗标本就足够了。相比之下,支气管灌洗在培养方面优于胃灌洗,但它们在直接涂片上的检出率相当。